Scientific Publications and Presentations
2007
V. V. Yuzhakov, “Advanced micro-needle Patch (AdminPatch™) for Minimally Invasive Transdermal Drug Delivery,” Invited Presentation at 1st Annual Skin Summit: Transdermal Drug Delivery & Development & Beyond, Philadelphia, PA, February 22-23, 2007.
2010
A paper about AdminPen devices
was published in Drug Delivery Technology.
A well-known journal Drug Delivery Technology recently published our
paper describing AdminPen devices. Please click on the following
link to read the published paper about AdminPen devices and the
enabling AdminPatch microneedle technology:
Yuzhakov, Vadim V. "The AdminPenTM Microneedle Device for Painless &
Convenient Drug Delivery." Drug Deliv. Technol 10.4 (2010): 32-36.
Full Text (PDF)
Scientific publications written by our academic customers summarizing studies successfully performed using our microneedle products.
2011
Lipika Chablani, Suprita Tawde,
Archana Akalkotkar and Martin J. D’Souza, Formulation of Novel
Particulate Breast Cancer Vaccines using Spray Drying and In Vivo
Evaluation of Vaccine Efficacy.
Full Text (PDF)
2012
Modepalli, Naresh, et al.
"Microporation and ‘Iron’tophoresis for Treating Iron Deficiency
Anemia." Pharmaceutical research (2013): 1-10.
Full Text (PDF)
2013
Singh, Neha D., and Ajay K. Banga.
"Controlled delivery of ropinirole hydrochloride through skin using
modulated iontophoresis and microneedles." Journal of drug targeting
21.4 (2013): 354-366.
Full Text (PDF)
Atul Nayak, Diganta B. Das, Goran T. Vladisavljevi
ć, "Microneedle-Assisted Permeation of Lidocaine Carboxymethylcellulose with Gelatine Co-polymer Hydrogel." Pharmaceutical Research, November 2013.Full Text (PDF)
Ita, Kevin, Nanik Hatsakorzian, and Vladimir
Tolstikov. "Microneedle-Mediated Delivery of Atenolol and Bisoprolol
Hemifumarate." Journal of Nanopharmaceutics and Drug Delivery 1.1
(2013): 38-44.
Full Text (PDF)
Juluri, Abhishek, et al. "Minimally invasive
transdermal delivery of iron–dextran." Journal of pharmaceutical
sciences 102.3 (2013): 987-993.
Full Text (PDF)
Tao Han, Diganta B. Das, "Permeability Enhancement
for Transdermal Delivery of Large Molecule Using Low-Frequency
Sonophoresis Combined with Microneedles." Journal of Pharmaceutical
Sciences, Vol. 102, 3614–3622 (2013).
Full Text (PDF)
Zhang, Dongwei, Diganta B. Das, and Chris D. Rielly.
"An Experimental Study of Microneedle‐Assisted Microparticle
Delivery." Journal of pharmaceutical sciences 102.10 (2013):
3632-3644.
Full Text (PDF)
Wenchao Sun, Zeynep Araci, Mohammed Inayathullah,
Sathish Manickam, Xuexiang Zhang, Marc A. Bruce, M. Peter
Marinkovich, Alfred T. Lane, Carlos Milla, Jayakumar Rajadas, Manish
J. Butte, Polyvinylpyrrolidone microneedles enable delivery of
intact proteins for diagnostic and therapeutic applications, Acta
Biomaterialia, Volume 9, Issue 8, August 2013, Pages 7767-7774.
Full Text (PDF)
Yuen, Clement, and Quan Liu. "Towards in vivo
intradermal surface enhanced Raman scattering (SERS) measurements:
silver coated microneedle based SERS probe." Journal of biophotonics
(2013).
Full Text (PDF)
Yuen, Clement, and Quan Liu. "Ag coated microneedle
based surface enhanced Raman scattering probe for intradermal
measurements." European Conferences on Biomedical Optics.
International Society for Optics and Photonics, 2013.
Full Text (PDF)
2014
Zhang, Dongwei, Diganta B. Das, and Chris D. Rielly.
"Microneedle Assisted Micro‐Particle Delivery from Gene Guns:
Experiments Using Skin‐Mimicking Agarose Gel." Journal of
pharmaceutical sciences (2014).
Full Text (PDF)
Monika Kaur, Kevin B. Ita, Inna E. Popova, Sanjai J.
Parikh, Daniel A. Bair, Microneedle-assisted delivery of verapamil
hydrochloride and amlodipine besylate, European Journal of
Pharmaceutics and Biopharmaceutics.
Full Text (PDF)
Cheung, K, Han, T, Das, DB. "Effect of Force of
Microneedle Insertion on the Permeability of Insulin in Skin,"
Journal of Diabetes Science and Technology (2014).
Full Text (PDF)
Dongwei Zhang, Chris D. Rielly, and Diganta B. Das.
"Microneedle-assisted microparticle delivery by gene guns:
experiments and modeling on the effects of particle
characteristics," Drug Delivery (2014).
Full Text (PDF)
Dongwei Zhang, Diganta B. Das, Chris D. Rielly.
"Microneedle assisted micro-particle delivery by gene guns:
Mathematical model formulation and experimental verification,"
Chemical Engineering Science (2014).
Full Text (PDF)
Dongwei Zhang, Diganta B. Das, "Microneedle assisted
microparticle delivery: experiments using a skin mimicking agarose
gel. The Third International Conference on Microneedles 2014,
University of Maryland School of Pharmacy in Baltimore, Maryland,
19th-21st May 2014, pp. 67-68.
Full Text (PDF)
2015
Leeladurga, V, Teja, UC, Sultana, SKA, Sudeep,
K, Anusha, VSS, Han, T, Nalluri, BN, Das, DB, Application of
Microneedle Arrays for Enhancement of Transdermal Permeation of
Insulin: In Vitro Experiments, Scaling Analyses and Numerical
Simulations, AAPS PharmSciTech, 2015.
Click here for Full Text (PDF)
Naresh Modepalli, HN Shivakumar, KL Paranjothy
Kanni, and S Narasimha Murthy, Transdermal iron replenishment
therapy, Therapeutic Delivery, 2015, Vol. 6, No. 6, Pages 661-668.
Click here for Full Text (PDF)
Ololade Olatunji, Richard T. Olsson,
Microneedles from Fishscale-Nanocellulose Blends Using Low
Temperature Mechanical Press Method, Pharmaceutics, 2015, 7(4),
363-378;
Click here for Full Text (PDF)
Hiep X. Nguyen, Ajay K. Banga, Enhanced skin
delivery of vismodegib by microneedle treatment, Drug Delivery and
Translational Research, August 2015, Volume 5, Issue 4, pp 407-423.
Click here for Full Text (PDF)
Karmen Cheung, Geoff West, Diganta Bhusan Das,
Delivery of large molecular protein using flat and short
microneedles prepared using focused ion beam (FIB) as a skin
ablation tool. Drug Delivery and Translational Research, August
2015, Volume 5, Issue 4, pp 462-467. DOI10.1007/s13346-015-0252-0
Click here for Full Text (PDF)
Nayak, A, Short, L, Das, DB (2015) Lidocaine
permeation from a lidocaine NaCMC:gel microgel formulation in
microneedle pierced skin: vertical (depth averaged) and horizontal
permeation profiles, Drug Delivery and Translational Research,
August 2015, Volume 5, Issue 4, pp 372-386.
DOI: 10.1007/s13346-015-0229-z
Click here for Full Text (PDF)
Ita, K. Transdermal Delivery of Drugs with
Microneedles—Potential and Challenges. Pharmaceutics 2015, 7,
90-105. doi:10.3390/pharmaceutics7030090
Click here for Full Text (PDF)
Nayak, A., Das, D. B., Chao, T. C. and Starov,
V. M. (2015), Spreading of a Lidocaine Formulation on Microneedle-Treated
Skin. J. Pharm. Sci.. doi: 10.1002/jps.24625
Click here for Full Text (PDF)
Tao Han and Diganta Bhusan Das, "A New
Paradigm for Numerical Simulation of Microneedle-Based Drug Delivery
Aided by Histology of Microneedle-Pierced Skin," Journal of
Pharmaceutical Sciences (2015)
Click here for Full Text (PDF)
Atul Nayak, Hiten Babla, Tao Han, and Diganta
Bhusan Das, "Lidocaine carboxymethylcellulose with gelatine
co-polymer hydrogel delivery by combined microneedle and
ultrasound," Drug Delivery (2015)
Click here for Full Text (PDF)
Buchi N. Nalluri, V Sai Sri Anusha, R Sri
Bramhini, J Amulya, S K Ashraf Sultana, U Chandra Teja and Digantha
B. Das, "In Vitro Skin Permeation Enhancement of Sumatriptan by
Microneedle Application" (2015), http://dx.doi.org/10.2174/1567201812666150304123150
http://www.eurekaselect.com/129118/article
2016
M. Gkikas, R. K. Avery, C. E. Mills, R.
Nagarajan, E. Wilusz, B. D. Olsen, Hydrogels That Actuate
Selectively in Response to Organophosphates, Adv. Funct. Mater.
2017, 27, 1602784.
Click here for Full Text (PDF)
Uppuluri, C., Shaik, A., Han, T. et al.,
Effect of Microneedle Type on Transdermal Permeation of Rizatriptan,
AAPS PharmSciTech (2017) 18: 1495.
Click here for Full Text (PDF)
Brendan Koch, Ilaria Rubino, Fu-Shi Quan,
Bongyoung Yoo, and Hyo-Jick Choi, Microfabrication for Drug
Delivery, Materials. 2016; 9(8):646
Click here for Full Text (PDF)
Suprita A. Tawde, Lipika Chablani, Archana
Akalkotkar, Martin J. D'Souza, Evaluation of microparticulate
ovarian cancer vaccine via transdermal route of delivery, Journal of
Controlled Release, Volume 235, August 2016, Pages 147-154
Click here for Full Text (PDF)
Buchi Naidu Nalluri, Sirivalli Kosuri, Sai Sri
Anusha Valluru, Chandra Teja Uppuluri, Ashraf Sultana Shaik,
Microneedle Assisted Transdermal Delivery of Levodopa, Indian
Journal of Pharmaceutical Education and Research., 2016;
50(2):287-294
Click here for Full Text (PDF)
Jennifer Zhang, Yan Wang, Jane Y. Jin, Simone
Degan, Russell P. Hall, Ryan D. Boehm, Panupong Jaipan, Roger J.
Narayan, Use of Drawing Lithography-Fabricated Polyglycolic Acid
Microneedles for Transdermal Delivery of Itraconazole to a Human
Basal Cell Carcinoma Model Regenerated on Mice, JOM, April 2016,
Volume 68, Issue 4, pp 1128-1133
Click here for Full Text (PDF)